IL23 Antikörper (AA 33-67)

Produktnummer ABIN4955879

Dieses Anti-IL23-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IL23 in WB. Geeignet für Maus.

Kurzübersicht für IL23 Antikörper (AA 33-67) (ABIN4955879)

Target: IL23 (Interleukin 23 (IL23))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL23 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IL23 Antikörper

Bindungsspezifität: AA 33-67

Kreuzreaktivität (Details): Expected species reactivity: Human

Aufreinigung: Antigen affinity

Immunogen: Amino acids 33-67 from the human protein were used as the immunogen for this IL-23 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the IL-23 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Antibody in 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the IL-23 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Details zu IL23

Target: IL23 (Interleukin 23 (IL23))

Andere Bezeichnung: IL-23

Hintergrund: Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak- Stat signaling cascade, stimulates memory rather than naive T- cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.

UniProt: Q9NPF7